Friday March 24, Florence

Friday March 24, Florence

00.01 - 23.59
WCO-IOF-ESCEO
08.00
Opening of the commercial exhibition
08.00 - 09.00
NON-SPONSORED SYMPOSIA
Meeting Room 1
Bone health: A reflection of the social mosaic
Chairperson: Gustavo Duque
Medieval evidence: Reconstructing social status from British Medieval skeletons Justyna Miszkiewicz
Contemporary evidence: Social gradient of osteoporosis Sharon Brennan‑Olsen
Epigenetic evidence: Chronic stress, inflammatory response and osteoporosis risk José Riancho
Moderated panel and audience questions  All
Meeting Room 2
IOF-ASBMR Symposium: Fracture risk assessment to target treatment: Effectiveness and cost-utility
Chairpersons: Bo Abrahamsen, John A. Kanis
Innovations in Approach to absolute risk assessment Cyrus Cooper
Prospective RCTs to evaluate effectiveness of such strategies Michael R. McClung
Economic Consequences of Treatment on basis of fracture risk assessment Eugene McCloskey
Meeting Room 3
Can exercise counter inflammation in the aged?
Chairperson: Ivan Bautmans
Immunosenescence and impact of exercise on cellular markers Hung Cao Dinh
Chronic low-grade inflammation and effects of exercise Keliane Liberman
Anti-inflammatory effects of resistance training: dose-response relationship Louis Nuvagah Forti
Meeting Room 4
Diagnosis and Management of Fibrous dysplasia / McCune Albright syndrome: A global patient pathway
Chairperson: Kassim Javaid
Introduction and Mission Statement of the International Consortium Kassim Javaid
Pathophysiology of skeletal and extra-skeletal manifestations of FD/MAS Neveen Hamdy
Consensus Clinical Care Pathway Kassim Javaid
Therapeutic options in FD/MAS (including surgical, skeletal and endocrine; current and future) Roland D. Chapurlat
Panel Discussion  All
Meeting Room 6
Global differences in dietary calcium intake
Chairperson: Bess Dawson‑Hughes
Introduction : including the role of calcium in bone growth and preservation Bess Dawson‑Hughes
Presentation of the Calcium Map results Ethan Balk
Presentation on the skeletal consequences of inadequate calcium intake Peter R. Ebeling
09.00 - 12.10
Auditorium A
SCIENTIFIC SESSION I
Chairpersons: John A. Kanis, Jean‑Yves Reginster
09.00
Auditorium A
Plenary Lecture 1
Who and when to treat in osteoporosis? John A. Kanis
09.30
Auditorium A
Oral communications selected from abstracts
09.30
Auditorium A
OC1
‣ ABALOPARATIDE-SC DECREASES VERTEBRAL, NONVERTEBRAL, MAJOR OSTEOPOROTIC, AND WRIST FRACTURES IN A SUBSET OF POSTMENOPAUSAL WOMEN AT HIGH RISK OF FRACTURE BY FRAX SCORE
Presenting author: E. V. McCloskey
Authors: L. A. Fitzpatrick, M. Hu, J. A. Kanis
09.40
Auditorium A
OC2
‣ ABALOPARATIDE-SC SIGNIFICANTLY REDUCES VERTEBRAL AND NONVERTEBRAL FRACTURES AND INCREASES BONE MINERAL DENSITY REGARDLESS OF BASELINE RISK: RESULTS FROM THE ACTIVE PHASE 3 CLINICAL TRIAL
Presenting author: L. A. Fitzpatrick
Authors: G. Hattersley, P. D. Miller, M. Hu, L. A. Russo, B. J. R. Riis, G. C.  Williams, F. Cosman
09.50
Auditorium A
OC3
‣ FRACTURE RISK REDUCTION WITH ROMOSOZUMAB: RESULTS OF A PHASE 3 STUDY IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS
Presenting author: F. Cosman
Authors: D. B. Crittenden, J. D. Adachi, N. Binkley, E. Czerwinski, S. Ferrari, L. C. Hofbauer, E. Lau, E. M. Lewiecki, A. Miyauchi, C. A. F. Zerbini, C. E. Milmont, L. Chen, J. Maddox, P. D.  Meisner, C. Libanati, A. Grauer
10.00
Auditorium A
OC4
‣ ROMOSOZUMAB RAPIDLY REDUCES CLINICAL VERTEBRAL FRACTURE INCIDENCE: RESULTS FROM THE FRAME STUDY
Presenting author: P. Geusens
Authors: M. Oates, A. Miyauchi, J. D. Adachi, M. Lazaretti‑Castro, P. R. Ebeling, C. A. Perez Nino, C. J. Milmont, A. Grauer, C. Libanati
10.10
Auditorium A
OC5
‣ EFFECT OF DENOSUMAB COMPARED WITH RISEDRONATE IN GLUCOCORTICOID-TREATED INDIVIDUALS: RESULTS FROM THE 12-MONTH PRIMARY ANALYSIS OF A RANDOMIZED, DOUBLE-BLIND, ACTIVE-CONTROLLED STUDY
Presenting author: K. G. Saag
Authors: R. B. Wagman, P. Geusens, J. D. Adachi, O. D.  Messina, R. Emkey, R. D. Chapurlat, N. S. Daizadeh, N. Pannacciulli, W. Lems
10.20
Auditorium A
OC6
‣ DISCONTINUATION OF DENOSUMAB AND ASSOCIATED VERTEBRAL FRACTURE INCIDENCE: ANALYSIS FROM FREEDOM AND ITS EXTENSION
Presenting author: S. Ferrari
Authors: J. P. Brown, N. Gilchrist, J.‑E. Beck Jensen, N. Pannacciulli, C. Recknor, C. Roux, S. Smith, O. Törring, I. Valter, R. B. Wagman, A. Wang, S. R. Cummings
10.30
Auditorium A
Plenary Lecture 2
What can we expect from bone forming agents in the management of osteoporosis? Serge Ferrari
11.00
Auditorium A
Presentation of the ESCEO-IOF-UCB Awards
Cyrus Cooper, Pascale Richetta
11.10
Auditorium A
Oral communications selected from abstracts
11.10
Auditorium A
OC7
‣ A NEW SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS OF LONG-TERM TRIALS OF PHARMACOLOGICAL TREATMENTS IN KNEE OSTEOARTHRITIS
Presenting author: L. C. Rovati
11.20
Auditorium A
OC8
‣ PHARMACEUTICAL-GRADE CHONDROITIN SULFATE IS AS EFFECTIVE AS CELECOXIB AND SUPERIOR TO PLACEBO IN SYMPTOMATIC KNEE OSTEOARTHRITIS: THE CHONDROITIN VS CELECOXIB VS PLACEBO TRIAL (CONCEPT)
Presenting author: J.‑Y. Reginster
Authors: J. Dudler, T. Blicharski, K. Pavelka, A. Lanzarotti
11.30
Auditorium A
OC9
‣ DISCOVERY OF A SMALL MOLECULE WNT PATHWAY INHIBITOR (SM04690) AS A POTENTIAL DISEASE MODIFYING TREATMENT FOR KNEE OSTEOARTHRITIS
Presenting author: N. E. Lane
Authors: V. Deshmukh, C. Barroga, H. Hu, S. KC, Y. Yazici
11.40
Auditorium A
OC10
‣ THE ASSOCIATION OF KNEE OSTEOARTHRITIS AND PREMATURE MORTALITY IN THE COMMUNITY: AN INTERNATIONAL INDIVIDUAL PATIENT LEVEL META-ANALYSIS IN SIX PROSPECTIVE COHORTS
Presenting author: K. M. Leyland
Authors: L. S.  Gates, M. T.  Sanchez‑Santos, D. Prieto‑Alhambra, A. Fudge, G. Collins, R. Cleveland, D. Felson, J. M. Jordan, L. F. Callahan, M. Nevitt, F. Saberi Hosnijeh, J. B. J. van Meurs, G. Jones, J. L. Newton, M. Batt, D. Altman, C. Cooper, N. K. Arden
11.50
Auditorium A
OC11
‣ OSTEOARTHRITIS INCREASES THE RISK OF CARDIOVASCULAR DISEASE: DATA FROM THE OSTEOARTHRITIS INITIATIVE
Presenting author: N. Veronese
Authors: T. Smith, J.‑Y. Reginster, S. Maggi
12.00
Auditorium A
OC12
‣ A RANDOMISED DOUBLE-BLIND PLACEBO-CONTROLLED CROSSOVER TRIAL OF ADALIMUMAB FOR EROSIVE HAND OSTEOARTHRITIS – THE HUMOR TRIAL
Presenting author: D. Aitken
Authors: L. L. Laslett, F. Pan, N. Bellamy, P. Bird, I. Haugen, G. Jones
14.00 - 15.00
Meeting Room 6
ESCEO-EUGMS HONORARY LECTURE
IL-17 in bone, cartilage and muscle diseases : State of the art and practical consequences for the patient Pierre Miossec
14.00 - 15.00
WHO SYMPOSIUM
Meeting Room 3
Integrated Care for Older People (launch of the ICOPE Guidelines)
Chairpersons: Roger Fielding, John Beard
Introduction John Beard
Community care model for optimizing trajectories of intrinsic capacity Islene Araujo de Carvalho
Screening for declines in intrinsic capacity in older people: a personalized approach to promote healthy ageing Matteo Cesari
Role of nutrition and physical exercise in maintaining intrinsic capacity Olivier Bruyère
Closing the evidence to practice gap: WHO ICOPE guideline recommendations Jotheeswaran Amuthavalli Thiyagarajan
Discussion
14.00 - 15.00
MEET-THE-EXPERT SESSIONS
Meeting Room 1
What can we expect from biomarkers in osteoarthritis?
Gabriel Herrero‑Beaumont
Meeting Room 2
Diabetes and bone
Serge Ferrari
Meeting Room 4
Bone fragility during childhood, young adulthood and before the menopause
Ego Seeman
14.00 - 15.00
ESCEO SYMPOSIUM
Meeting Room 5
Identification and management of patients at imminent risk of osteoporotic fracture
Chairpersons: Bernard Cortet, Bo Abrahamsen
Welcome and scope of the problem Cyrus Cooper
How can we define a patient at imminent risk of fracture? Nicholas Harvey
Efficacy of currently available treatments in patients at imminent risk of fracture Thierry Thomas
Discussion : Leader: Salvatore Minisola
Wrap-up and conclusion Cyrus Cooper
Panel: Bo Abrahamsen, Maria Luisa Brandi, Jorge Cannata Andia, Cyrus Cooper, Bernard Cortet, Hans Peter Dimai, Serge Ferrari, Peyman Hadji, Nicholas Harvey, John A. Kanis, Marius Kraenzlin, Andreas Kurth, Andrea Laslop, Eugene McCloskey, Salvatore Minisola, Jean‑Yves Reginster, René Rizzoli, Thierry Thomas
14.00 - 15.00
Poster area
Poster Viewing Session I
14.00 - 15.10
Podium
Oral presentation of selected posters
Chairperson: Elaine M. Dennison
14.00
Podium
P564
‣ BONE MICROARCHITECTURE ANALYSIS BY HR-PQCT OF YOUNG ADULTS WITH KLINEFELTER SYNDROME REVEALED SEVERE BONE FRAGILITY
Presenting author: C. B. Confavreux
Authors: A. Piot, P. S. Szulc, J. Baccheta, S. Ailloud, H. Lejeune, R. D. Chapurlat, S. Boutroy, I. Plotton
14.07
Podium
P810
‣ FACTORS INFLUENCING END OF LIFE COST AND SURVIVAL IN ELDERLY OSTEOPOROTIC FRACTURE COHORTS
Presenting author: T. D. Tosteson
Authors: Q. Yang, A. N. Tosteson, J. Munson, Z. Li
14.14
Podium
P133
‣ PREPUBERTAL IMPACT OF PROTEIN INTAKE AND PHYSICAL ACTIVITY ON WEIGHT BEARING PEAK BONE MASS AND STRENGTH IN HEALTHY MALES
Presenting author: T. Chevalley
Authors: J.‑P. Bonjour, M.‑C. Audet, F. Merminod, B. van Rietbergen, R. Rizzoli, S. Ferrari
14.21
Podium
P667
‣ MUSCLE STRENGTH AND PHYSICAL PERFORMANCE FROM MIDLIFE AND BONE HEALTH IN EARLY OLD-AGE: THE MRC NATIONAL SURVEY OF HEALTH AND DEVELOPMENT
Presenting author: K. A. Ward
Authors: D. Kuh, S. Muthuri, A. Moore, C. Cooper, R. Cooper
14.28
Podium
P375
‣ RELATIONSHIPS BETWEEN MARKERS OF INFLAMMAGING AND BONE MICROARCHITECTURE: FINDINGS FROM THE HERTFORDSHIRE COHORT STUDY
Presenting author: N. R. Fuggle
Authors: L. D. Westbury, H. E. Syddall, N. A. Duggal, E. M. Dennison, J. Lord, C. Cooper
14.35
Podium
P841
‣ ANALYZING THE CORTICAL AND TRABECULAR BONE OF TENOFOVIR-TREATED HIV PATIENTS USING 3D-DXA.
Presenting author: R. Güerri‑Fernandez
Authors: L. H. Humbert, X. Nogués, N. Garcia‑Giralt, L. Mellibovsky, H. Knobel, A. Diez‑Perez
14.42
Podium
P756
‣ CLUSTER ANALYSIS OF BONE MICROARCHITECTURE FROM HIGH RESOLUTION PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY (HR-PQCT) AND FRACTURE IN THE GLOW STUDY
Presenting author: A. E. Litwic
Authors: L. D. Westbury, D.E. Robinson, K. A. Ward, C. Cooper, E. M. Dennison
14.49
Podium
P1040
‣ THE ELEVATED LEVELS OF BONE TURNOVER MARKERS IN YOUNG MEN ARE ASSOCIATED WITH BONE LOSS: A LONGITUDINAL STUDY IN HEALTHY YOUNG ADULTS
Presenting author: C. Verroken
Authors: S. Goemaere, H. Zmierczak, K. Toye, B. Lapauw, J.‑M. Kaufman
14.56
Podium
P676
‣ EFFECTS OF ABALOPARATIDE-SC ON BONE MINERAL DENSITY AND RISK OF FRACTURE IN POSTMENOPAUSAL WOMEN AGED 80 YEARS OR OLDER WITH OSTEOPOROSIS
Presenting author: M. R. McClung
Authors: N. C. Harvey, L. A. Fitzpatrick, P. D. Miller, G. Hattersley, Y. Wang, F. Cosman
15.03
Podium
P747
‣ COST-EFFECTIVENESS OF COMPLYING WITH TREATMENT GUIDELINES IN SWEDEN
Presenting author: E. Jonsson
Authors: A. Hansson‑Hedblom, O. Ljunggren, K. Åkesson, A. Spangeus, F. Borgström, J. A. Kanis
15.00 - 16.45
Meeting Room 6
IOF COMMITTEE OF NATIONAL SOCIETIES SPECIAL PLENARY SESSION
Chairperson: Jean‑Yves Reginster
15.03
Meeting Room 6
OCs1
‣ BONE MINERAL DENSITY AT PATIENTS OF EARLY ONSET RHEUMATOID ARTHRITIS
Presenting author: B. Rexhepi
Authors: S. Rexhepi, M. Rexhepi, V. Sahatçiu‑Meka, M. Qorolli
15.11
Meeting Room 6
OCs2
‣ ASSOCIATION BETWEEN GENETIC FACTORS OF OSTEOPOROSIS AND FRAX® CALCULATED TEN-YEAR FRACTURE PROBABILITY
Presenting author: P. Marozik
Authors: E. Rudenka, K. Liaonchyk, A. Rudenka, O. Samakhavets
15.19
Meeting Room 6
OCs3
‣ IN-OFFICE PROTEOMIC PLATFORM FOR BONE MARKER MEASUREMENT
Presenting author: B. Larijani
Authors: P. Khashayar, G. Amoabediny, J. Vanfleteren
15.27
Meeting Room 6
OCs4
‣ BODY MASS INDEX, VITAMIN D DEFICIENCY AND PHYSICAL ACTIVITY IN OSTEOPOROSIS
Presenting author: R. Alimanovic‑Alagic
Authors: S. Sokolovic, M. Vrcic, A. Kapetanovic, E. Rabari, S. Hodzic
15.35
Meeting Room 6
OCs5
‣ COMPARATIVE STUDY OF FRAX® SCORE IN ECUADORIAN POPULATION
Presenting author: O. D.  Messina
Authors: G. Maldonado, C. Paredes, R. Guerrero, M. Mieles, C. Rios
15.43
Meeting Room 6
OCs6
‣ DEVELOPMENT AND VALIDATION OF ANTHROPOMETRIC PREDICTION MODEL FOR ESTIMATION OF MUSCLE MASS IN THE ELDERLY
Presenting author: B. Larijani
Authors: R. Heshmat, G. Shafiee, A. Keshtkar
15.51
Meeting Room 6
OCs7
‣ IMPORTANCE OF THE JOURNAL AND WEBSITE BONE HEALTH FOR PATIENTS WITH OSTEOPOROSIS AND OTHER MUSCULOSKELETAL DISEASES
Presenting author: M. Mukane
Authors: S. Upmale, M. Mukans, I. Rasa
15.59
Meeting Room 6
OCs8
‣ TBS, VFA AND HANDGRIP IN A GROUP OF POSTMENOPAUSAL WOMEN WITH VERTEBRAL FRACTURE
Presenting author: E. Czerwinski
Authors: J. Amarowicz, A. Kumorek, M. Warzecha
16.07
Meeting Room 6
OCs9
‣ DISCRIMINATIVE POWER OR ROMANIAN VERSION OF SARQOL QUESTIONNAIRE: PRELIMINARY RESULTS
Presenting author: A. I. Gasparik
Authors: G. Mihai, C. Sucaliuc, I. M. Pascanu
16.15
Meeting Room 6
OCs10
‣ IN PATIENT CARE FOR DIABETIC AND NON-DIABETIC PATIENTS WITH OSTEOPOROTIC HIP FRACTURES IN A FRACTURE LIAISON SERVICE AT AN ASIAN HOSPITAL: BRINGING THE BURDEN INTO THE SPOTLIGHT
Presenting author: M. Chandran
Authors: X. F. Huang, K. Choo, D. Tay, Y. Hao
16.23
Meeting Room 6
OCs11
‣ BALLOON KYPHOPLASTY COMPARED TO PERCUTANEOUS VERTEBROPLASTY: WHAT IS THE EVIDENCE?
Presenting author: P. R. Ebeling
Authors: A. J.  Rodriguez, H. A. Fink, L.  Mirigian, N. Guanabens, R. Eastell, K. Åkesson, D. C.  Bauer
16.35
Meeting Room 6
Presentation of the IOF Committee of National Societies Medal
Jean‑Yves Reginster
15.00 - 17.00
Auditorium A
SCIENTIFIC SESSION II
Chairpersons: Cyrus Cooper, René Rizzoli
15.00
Auditorium A
Plenary Lecture 3
Implication of bone biomechanics in daily practice Mary L. Bouxsein
15.30
Auditorium A
Presentation of the IOF President's Awards
John A. Kanis
15.40
Auditorium A
Oral communications selected from abstracts
15.40
Auditorium A
OC13
‣ PREMENOPAUSAL WOMEN WITH EARLY BREAST CANCER TREATED BY OESTRADIOL SUPPRESSION HAVE SEVERELY DETERIORATED BONE MICROSTRUCTURE
Presenting author: S. K. Ramchand
Authors: E. Seeman, X.‑F. Wang, A. Ghasem‑Zadeh, P. A. Francis, E. J. Ponnusamy, M. S.  Bardin, M. Bui, J. D.  Lajac, M. Grossmann
15.50
Auditorium A
OC14
‣ WOMEN IDENTIFIED AT HIGH RISK BASED ON FRAX HIP FRACTURE PROBABILITY ARE RESPONSIVE TO APPROPRIATE OSTEOPOROSIS MANAGEMENT: ANALYSIS FROM THE SCOOP STUDY OF POPULATION SCREENING
Presenting author: E. V. McCloskey
Authors: N. C. Harvey, H. Johansson, L. Shepstone, E. Lenaghan, C. Cooper, J. A. Kanis
16.00
Auditorium A
OC15
‣ CAN INDIVIDUALISED RISK FEEDBACK PRODUCE LONG-TERM HEALTH BENEFITS? A 10-YR FOLLOW-UP OF A 2-YR RANDOMISED CONTROLLED TRIAL OF FEEDBACK OF FRACTURE RISK
Presenting author: F. Wu
Authors: K. Wills, L. L. Laslett, M. Riley, B. Oldenburg, G. Jones, T. Winzenberg
16.10
Auditorium A
OC16
‣ MOBILITY RELATED RISK FACTORS PREDICT INCIDENT FRACTURES INDEPENDENTLY OF FRAX: THE OSTEOPOROTIC FRACTURES IN MEN (MROS) STUDY
Presenting author: N. C. Harvey
Authors: A. Odén, E. Orwoll, J. Lapidus, T. Kwok, M. Karlsson, B. Rosengren, O. Ljunggren, C. Cooper, J. A. Kanis, C. Ohlsson, D. Mellström, H. Johansson, E. V. McCloskey
16.20
Auditorium A
OC17
‣ IMMINENT RISK OF HIP FRACTURE AFTER RECENT (SENTINEL) FRACTURE – COMPARISON OF SENTINEL FRACTURE SITES (REYKJAVIK STUDY)
Presenting author: H. Johansson
Authors: K. Siggeirsdottir, N. C. Harvey, A. Odén, V. Gudnason, E. V. McCloskey, G. Sigurdsson, J. A. Kanis
16.30
Auditorium A
Plenary Lecture 4
Emerging treatments for the management of osteoarthritis Tim McAlindon